The Vall d´Hebron Institute of Oncology (VHIO) Seeks a “Bioinformatician for Prostate Cancer Genomics Research”.
Reference: Ref. 01-2021
Application deadline: Jan-Feb 2021
Number of vacancies: 1
Job description:
A position for a bioinformatics researcher is available for Q1-2021 at the Vall d’Hebron Institute of Oncology’s Prostate Cancer Translational Research Group (PI: Joaquin Mateo). Our group focuses on studying and testing hypothesis-based targeted therapy in prostate cancer and we are especially committed to applying the potential clinical value of our findings to clinical trials. Currently ongoing projects in the lab are focused in: 1) derivation and clinical validation of genomics signatures based whole-exome, whole-genome and RNA sequencing of primary and metastatic prostate cancer biopsies to identify prostate cancers with clinically-relevant DNA repair deficiencies; 2) multi-compartmental characterisation of liquid biopsies in prostate cancer, including comparative analysis of cell-free tumor DNA, circulating tumor cells and tumor-derived exosomal DNA longitudinally in response and at progression of anticancer therapies; 3) discovery of clinico-genomic correlates based on exploiting open knowledgebases as well as privately owned databases from collaborators.
We are seeking an organized, motivated and team-oriented bioinformatician with previous experience in cancer genomics and with the desire to work in a multidisciplinary team focused in translational research.
Requirements:
The following requirements are mandatory:
- Degree in bioinformatics, computer science, computational biology or similar. Applicants with degrees in biotechnology, biology or other life sciences will be considered providing they can demonstrate expertise in bioinformatics/computational genomics.
- Experience in cancer genomics.
- This position is intended for postdoctoral researches with a PhD in biomedical/computer sciences who can progressively become independent in developing academic research projects in line with the group priorities. Applicants who do not hold a PhD degree may be considered in exceptional situations.
- Experience in processing and analysing next-generation sequencing data including whole-exome, whole-genome and RNA sequencing.
- Experience in visualization tools for genomics data.
- Fluent in R and/or Python, other programming languages will also be favoured.
- The candidate is expected to be able to communicate well in English, even if it is not his/her first language.
Additional information:
In principle, this is a 3 years project, although the contract will be renewed based on positive annual appraisals.
Salary to be discussed according to previous experience.
The salary will be fully covered from existing grants from the US CDMRP-Department of Defense and AECC, although in the long-term the candidate is expected to pursue grant applications to develop their own academic projects with the support of the group.
Application:
Applicants should send a full Curriculum Vitae and a cover letter to selecciorrhh@vhio.net. Please also attach a letter of recommendation to your application.
About VHIO:
Under the leadership of Josep Tabernero, the Vall d’Hebron Institute of Oncology (VHIO), has established itself as a comprehensive cancer center of proven excellence internationally. It is also thanks to VHIO’s optimal organizational structure based on a purely multidisciplinary and translational model that VHIO talents continue to anticipate and tackle the many unresolved questions in combatting this multifaceted and heterogeneous disease.
Located within the Vall d’Hebron Barcelona Hospital Campus, our researchers closely collaborate and interact with Vall d’Hebron physician-scientists. Translational science and clinical research are therefore tightly connected which promotes superb interaction and teamwork which, in turn, accelerates the bench-bedside-bed cycle of knowledge. This privileged environment affords VHIO direct access to patients as well as the entire spectrum of oncology professionals who care for them, and a second-to-none appreciation of how cancer science can translate into more powerful, targeted treatments and better practice for the care of patients.
VHIO’s pioneering model and programs, coupled with its belief in combining strengths through cross-border collaborations, continue to spur advances in reversing cancer resistance, halting metastatic spread, and more effectively treating even the most undruggable tumor types.
VHIO’s translation toward precision oncology: https://www.vhio.net
Vall d’Hebron Institute Oncology (VHIO) endorses the Requirements and Principles of the European Charter for Researchers, the Code of Conduct for the Recruitment of Researchers promoted by the European Commission and follows Equal Opportunities policies.
On 10th April 2018 VHIO was awarded the “HR Excellence in Research” logo. Our Institute was consequently granted permission to use the HR Excellence in Research Award logo as demonstration of its stimulating and favourable work environment in line with the Charter & Code.
