Biosketch Isabel Puig Borreil

Isabel Puig Borreil
Current position
Curriculum Summary

I obtained my BSc in Biology in June 2000 at the University of Barcelona. My undergraduate (1999-2000) and predoctoral research experience (2000-2005) was acquired entirely in the laboratory of Dr. Antonio García de Herreros at the “Instituto Municipal de Investigación Médica” (IMIM) in Barcelona with a predoctoral fellow (FPU). From 2005 to 2009, I was a postdoctoral fellow in the laboratory of Dr. Lionel Larue at the “Institute Curie” in Orsay (Paris-France).

In 2009, I joined the group Stem Cells and Cancer, led by Dr. Héctor G. Palmer, at Vall d’Hebron Institute of Oncology (VHIO). I am currently Senior Investigator and the main focus of my research is deciphering the molecular mechanisms involved in resistance to cancer therapy.

In summary, I published 19 manuscripts in a high impact scientific journals (18 in the first quartile), 8 of them as first or co-first author. I obtained 2 competitive Project-Fellowships from Fundación científica de la Asociación Española contra el Cáncer (FcAECC): Ayuda para Investigadores en Oncología-AIO 2010, and Investigador AECC 2016. In 2020, I obtained 3 competitive Grants from FcAECC and Fundación La Caixa as PI or co-PI to lead (i) the development of TET2 modulators as a new anti-tumoural therapy to fight cancer (INNOVA AECC 2020, co-ordinator: Héctor G Palmer), (ii) the study of autophagy as a molecular mechanism of drug resistance in the context of dormant tumour cells (Ideas Semilla AECC 2020), and (iii) the development of a new strategy to enhance the therapeutic efficacy of CAR cells (CaixaImpulse Validate, Co-ordinator: Carlos Galdeano). Furthermore, I have co-supervised a PhD thesis (Estefania Cuesta, 2019) and I am currently supervising a new one (Cándida Salvans), and I also tutored some MSc’s students and their projects. Finally, I am member of the European Association for Cancer Research (EACR), the “Asociación Española de Investigación sobre el Cáncer” (ASEICA) and the network Women in Autophagy (WIA).