Biosketch Mate Maus

Mate Maus
matemaus@vhio.net
Posición actual
  • Jefe del Grupo de Envejecimiento y Cáncer
Formación académica
  • Doctorado en Inmunología, Universidad Eötvös Loránd, Hungría, 2010
  • Grado en Ciencias de la Vida, Universidad Eötvös Loránd, Hungría, 2006
Áreas de investigación
  • Envejecimiento del microentorno y cáncer
  • Inmunosenescencia y cáncer
  • Detección de nutrientes en la senescencia celular en el envejecimiento y el cáncer
Premios y becas
  • 2022 – 2027     Beca Ramón y Cajal,Investigador principal: Mate Maus; afiliación: IRB Barcelona; dotación económica: 219 250 €
Publicaciones
  • Maus M, López-Polo V, Lafarga M, Aguilera M, De Lama E, Meyer K, Manonelles A, Sola A, López Martínez C, López-Alonso I, Hernández-Gonzales F, Chaib S, Rovira M, Sánchez M, Faner R, Agusti A, Prats N, Albaiceta G, Cruzado JM, Serrano M. Iron accumulation drives fibrosis, senescence, and the senescence-associated secretory phenotype. bioRxiv 2022 https://doi.org/10.1101/2022.07.29.501953
  • Maus M, Serrano M. A novel redox cycle diverts cells from oncogene-induced senescence into cancer. Mol Cell. 16 sept. 2021;81(18):3672-3674.
  • Kahlfuss S, Kaufmann U, Concepción AR, Noyer L, Raphael D, Vaeth M, Yang J, Pancholi P, Maus M, Muller J, Kozhaya L, Khodadadi-Jamayran A, Sun Z, Shaw P, Unutmaz D, Stathopulos PB, Feist C, Cameron SB, Turvey SE, Feske S. STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells. EMBO Mol Med. 7 ago. 2020;12(8):e11592.
  • Saint Fleur-Lominy S* y Maus M*, Vaeth M, Lange I, Zee I, Suh D, Liu C, Wu X, Tikhonova A, Aifantis I, Feske S. STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia. Cell Rep. 11 sept. 2018;24(11):3045-3060.e5. (*contribución por igual)
  • Vaeth M* y Maus M*, Klein-Hessling S, Freinkman E, Yang J, Eckstein M, Cameron S, Turvey SE, Serfling E, Berberich-Siebelt F, Possemato R, Feske S. Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming. Immunity. 17 oct. 2017;47(4):664-679.e6. (*contribución por igual)
  • Maus M, Cuk M, Patel B, Lian J, Ouimet M, Kaufmann U, Yang J, Horvath R, Hornig-Do HT, Chrzanowska-Lightowlers ZM, Moore KJ, Cuervo AM, Feske S. Store-Operated Ca2+ Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism. Cell Metab. 7 mar. 2017;25(3):698-712.
  • Vaeth M, Zee I, Concepcion AR, Maus M, Shaw P, Portal-Celhay C, Zahra A, Kozhaya L, Weidinger C, Philips J, Unutmaz D, Feske S. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 1 ago. 2015;195(3):1202-17.
  • Maus M, Jairaman A, Stathopulos PB, Muik M, Fahrner M, Weidinger C, Benson M, Fuchs S, Ehl S, Romanin C, Ikura M, Prakriya M, Feske S. Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation. Proc Natl Acad Sci U S A. 12 may. 2015;112(19):6206-11.
  • Maus M, Medgyesi D, Kiss E, Schneider AE, Enyedi A, Szilágyi N, Matkó J, Sármay G. B cell receptor-induced Ca2+ mobilization mediates F-actin rearrangements and is indispensable for adhesion and spreading of B lymphocytes. J Leukoc Biol. 2013;93(4):537-47.
  • Maus M, Medgyesi D, Kövesdi D, Csuka D, Koncz G, Sármay G. Grb2 associated binder 2 couples B-cell receptor to cell survival. Cell Signal. Feb 2009;21(2):220-7.
  • Sármay G, Angyal A, Kertész A, Maus M, Medgyesi D. The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling. Immunol Lett. 15 abr. 2006;104(1-2):76-82.