The Vall d´Hebron Institute of Oncology (VHIO) Seeks a “Staff researcher (NGS) at the Prostate Cancer Translational Research Group”
Reference: Ref. 23-2023
Application deadline: until position filled.
Number of vacancies: 1
Job description:
Background:
The Prostate Cancer Translational Research Group at VHIO focuses on studying and testing hypothesis-based targeted therapies in prostate cancer and we are especially committed to applying the potential clinical value of our findings to clinical trials. Interrogation of clinical samples and correlative studies are central to our research strategy. More details on our research can be found in: https://vhio.net/pf/prostate-cancer-translational-research-group/
Description of the position:
The Staff Researcher for the NGS projects of the group should be a dynamic and team-oriented scientist with two main responsibilities:
1) Overseeing end-to-end the pursue of NGS experiments at our group, ensuring the highest standards in research (quality, ethics and reproducibility) and efficient use of resources
2) Lead the implementation of innovative NGS technologies that enable the launch of new projects in the group.
The Staff Researcher (SF) will report directly to the Group Leader (GL), and will be managing the wet- and dry-lab technicians involved in clinical samples processing/NGS assays.
Specific tasks and responsabilities are listed below:
- Oversight and optimization of NGS projects
- To train and supervise the wet-laboratory technicians and students in NGS assays, to ensure the highest quality in delivering NGS assays in the group
- To participate in the design and planning of experiments using NGS to optimize projects.
- Coordinate and monitor the execution of NGS projects, with continuous follow up and reporting to the team leader.
- Be the lead contact for discussion with external partners involved in NGS projects (collaborators and service providers)
- Create, review and maintain documentation related to NGS projects in the lab, including: samples registry, electronic lab books, specific project templates…
- Occasionally, depending on workloads and project deadlines, the SF would provide hands-on support in wet-lab pipelines.
- Implementation of new NGS technologies in the lab
- Develop & standardize new wet-lab pipelines prior to implementing them in research projects from the group. In particular, and funded by a recent award by the DoD CDMR Prostate Cancer Program for the 2023-2027 period, we are seeking to implement spatial transcriptomics and single-cell RNAseq analysis workflows in the group.
- Work with the GL and postdoctoral researchers in the identification of the optimal technical solutions for new NGS project, being integral to the definition of scopes and objectives, conducting the necessary work to ensure technical feasibility and customized solutions when needed.
Requirements:
- PhD in biomedical sciences with at least 3 years as post-doctoral experience.
- Expertise in next-generation sequencing assays, including DNA and RNA library preparation from clinical samples, ideally having demonstrated skills for project management in the past.
- Prior experience in the field of cancer research
- The candidate is expected to be proficient communicating in English, as it is the working language in the lab.
Additional information:
- Experience in spatial transcriptomics and/or single-cell RNAseq assays.
- Training in Good Clinical Practice for managing clinical research specimens.
- Basic/intermediate level bionformatics skills for an end-to-end supervision of NGS projects in the team.
Contract conditions:
Permanent contract with an initial test period according to current legal framework and institutional standards. Funding is secured for at least 4 years.
Start date: As soon as possible.
Remuneration will depend on experience and skills. Salary ranges are consistent with our Collective Agreement pay scale.
Application:
Potential candidates should submit a curriculum vitae and a letter of intent via email to selecciorrhh@vhio.net, including the reference “Ref. 23-2023” in the subject line of your email.
About VHIO:
Under the leadership of Josep Tabernero, the Vall d’Hebron Institute of Oncology (VHIO), has established itself as a comprehensive cancer center of proven excellence internationally. It is also thanks to VHIO’s optimal organizational structure based on a purely multidisciplinary and translational model that VHIO talents continue to anticipate and tackle the many unresolved questions in combatting this multifaceted and heterogeneous disease.
Located within the Vall d’Hebron Barcelona Hospital Campus, our researchers closely collaborate and interact with Vall d’Hebron physician-scientists. Translational science and clinical research are therefore tightly connected which promotes superb interaction and teamwork which, in turn, accelerates the bench-bedside-bed cycle of knowledge. This privileged environment affords VHIO direct access to patients as well as the entire spectrum of oncology professionals who care for them, and a second-to-none appreciation of how cancer science can translate into more powerful, targeted treatments and better practice for the care of patients.
VHIO’s pioneering model and programs, coupled with its belief in combining strengths through cross-border collaborations, continue to spur advances in reversing cancer resistance, halting metastatic spread, and more effectively treating even the most undruggable tumor types.
VHIO’s translation toward precision oncology: https://www.vhio.net
Vall d’Hebron Institute Oncology (VHIO) endorses the Requirements and Principles of the European Charter for Researchers, the Code of Conduct for the Recruitment of Researchers promoted by the European Commission and follows Equal Opportunities policies.
On 10th April 2018 VHIO was awarded the “HR Excellence in Research” logo. Our Institute was consequently granted permission to use the HR Excellence in Research Award logo as demonstration of its stimulating and favourable work environment in line with the Charter & Code.
