The Vall d´Hebron Institute of Oncology (VHIO) Seeks a “Research Technician: Prostate Cancer models, In-Vivo and In-Vitro experiments”
Reference: Ref. 10-2022
Application deadline: 15/04/2022
Number of vacancies: 1
The Prostate Cancer Translational Research Group is seeking an experienced Research Technician to join our lab.
Our group mission is to improve advanced prostate cancer management through a better understanding of tumour response and resistance mechanisms and by correlating clinical and molecular data to advanced towards a more precise patient care. Our multidisciplinary team is composed by biomedical scientists, bioinformaticians, medical oncologists and clinical data specialists.
Find more about our research here: https://www.vhio.net/prostate-cancer-translational-research-group/
The successful candidate will form an integral part of the preclinical team in our group, which is focused on understanding how prostate cancers adapt to systemic therapies, with a particular interest in the DNA damage response regulation and the emergence of senescent phenotypes. To do so, we combine patient-derived models, organoid/cell culture systems, Omics and functional tools (CRISPR/Cas9, transcriptional activity reporters, etc).
The position will include support for scientific training when required and opportunities to participate and lead new projects.
- The successful candidate will perform in vivo work and cellular biology techniques to support projects within the research lines of the lab as well as projects in collaboration with pharma companies. We expect the candidate to work independently and to be able to set up and maintain the lab’s experimental pipelines.
- Research activities may include (but are not limited to) .
In vivo: Drug administration (oral gavage, ip adminsitration), minor surgeries (orchiectomy, tumor transplantation) and tissue processing.
In vitro: 2D/3D cell culture, lentiviral infections, DNA/RNA extraction, qRT-PCR, immunoblotting and proliferation/viability assays.
- The candidate will be required to design and execute drug sensitivity experiments in in vivo models under minimum supervision.
- The candidate will also manage the histological characterization of all generated patient-derived models in collaboration with our group’s pathologist.
- The candidate must be committed to learning new techniques and concepts and to contribute with new ideas on topics related to the lab’s research goals.
- Contribute to training undergraduate students and incoming lab members.
- Prior experience working with laboratory mouse models is mandatory, and knowledge in cellular biology techniques and cell culture will be highly valued.
- We required a very organized, pro-active, team-oriented individual able to coordinate and perform multiple tasks.
- Full accreditation for working with mouse models.
- Background in cancer and prior lab technician experience, and/or PhD/post-doctoral training will be positively evaluated.
- Full time position.
- Salary will be estimated according to profile and experience.
- Start date: Between March and May 2022 (flexible).
- Potential candidates should submit a curriculum vitae, letter of intent, and at least one reference using the form below or via email to firstname.lastname@example.org, including the reference “Ref. 10-2022” in the subject line of your email. Review of applications will commence immediately; interviews will be arranged with short-listed candidates.
Under the leadership of Josep Tabernero, the Vall d’Hebron Institute of Oncology (VHIO), has established itself as a comprehensive cancer center of proven excellence internationally. It is also thanks to VHIO’s optimal organizational structure based on a purely multidisciplinary and translational model that VHIO talents continue to anticipate and tackle the many unresolved questions in combatting this multifaceted and heterogeneous disease.
Located within the Vall d’Hebron Barcelona Hospital Campus, our researchers closely collaborate and interact with Vall d’Hebron physician-scientists. Translational science and clinical research are therefore tightly connected which promotes superb interaction and teamwork which, in turn, accelerates the bench-bedside-bed cycle of knowledge. This privileged environment affords VHIO direct access to patients as well as the entire spectrum of oncology professionals who care for them, and a second-to-none appreciation of how cancer science can translate into more powerful, targeted treatments and better practice for the care of patients.
VHIO’s pioneering model and programs, coupled with its belief in combining strengths through cross-border collaborations, continue to spur advances in reversing cancer resistance, halting metastatic spread, and more effectively treating even the most undruggable tumor types.
VHIO’s translation toward precision oncology: https://www.vhio.net
Vall d’Hebron Institute Oncology (VHIO) endorses the Requirements and Principles of the European Charter for Researchers, the Code of Conduct for the Recruitment of Researchers promoted by the European Commission and follows Equal Opportunities policies.
On 10th April 2018 VHIO was awarded the “HR Excellence in Research” logo. Our Institute was consequently granted permission to use the HR Excellence in Research Award logo as demonstration of its stimulating and favourable work environment in line with the Charter & Code.